Notre Dame Vs Pittsburgh Prediction 2025 Football. The total opened at 44.5 points and has stayed the same. And then there were four.

Preview the october 28 matchup between the notre dame fighting irish and pittsburgh panthers with predictions, odds, over/under, spread, betting lines and more. For the orange bowl 2025, kaylor is going under the total (45.5), despite it being a full eight points lower than the other college football playoff.